منابع مشابه
Interleukin-32 in Inflammatory Autoimmune Diseases
Interleukin-32 (IL-32) is a cytokine inducing crucial inflammatory cytokines such as tumor necrosis factor-α (TNFα) and IL-6 and its expression is elevated in various inflammatory autoimmune diseases, certain cancers, as well as viral infections. IL-32 gene was first cloned from activated T cells, however IL-32 expression was also found in other immune cells and non-immune cells. IL-32 gene was...
متن کاملInterleukin-32 Promotes Osteoclast Differentiation but Not Osteoclast Activation
BACKGROUND Interleukin-32 (IL-32) is a newly described cytokine produced after stimulation by IL-2 or IL-18 and IFN-gamma. IL-32 has the typical properties of a pro-inflammatory mediator and although its role in rheumatoid arthritis has been recently reported its effect on the osteoclastogenesis process remains unclear. METHODOLOGY/PRINCIPAL FINDINGS In the present study, we have shown that I...
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This article has no abstract.
متن کاملEffects of leukotriene B4 on interleukin-32, interferon-γ and chemokines in rats with rheumatoid arthritis
The objective of this study was to investigate the effects of leukotriene B4 (LTB4) on the expression of interleukin-32 (IL-32) interferon-γ (IFN-γ) and chemokine monocyte chemoattractant protein (MCP-1) and macrophage inhibitory protein (MIP-1α) in rheumatoid arthritis (RA). The rat model of RA collagen induced-arthritis (CIA) was established. The levels of LTB4, interleukin-32, IFN-γ and chem...
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ژورنال
عنوان ژورنال: Immunity
سال: 2005
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2004.12.003